Welcome to Read Book Online

DOWNLOAD
Author by : Jerome Levine
Languange Used : en
Release Date : 1979
Publisher by :

ISBN : UCR:31210023565276

...

DOWNLOAD
Author by : Marc Hertzman
Languange Used : en
Release Date : 2010-03-16
Publisher by : John Wiley & Sons

ISBN : 0470749172

Although clinical trials were virtually unheard of in psychiatry for many years, they are now the gold standard for judging whether drugs are safe and useful. But should they be? What is the true status of clinical trials? Even when they ostensibly demonstrate a benefit of a certain treatment, the strict patient selection criteria, poor compliance and high drop-out rate leave the conclusions open to question. Are the new treatments really better or more cost-effective than the old? Do they have fewer side effects? In this book the authors take a critical look at recent developments and present a series of trenchant and challenging observations. Section I examines the significant changes in law and the regulatory environment that have occurred during the past ten years. Has fossilization handicapped the US Food and Drug Administration in promoting treatment advances? How can the plethora of findings be regulated? This is particularly pertinent in genomic studies and there are two chapters addressing the impact of genomics on psychiatric research. This section also addresses the role of women in drug trials – a group long excluded but now demanding a part, for without testing how can optimal treatments be devised? The next two Sections highlight clinical trials in the major areas of psychiatric pharmacological treatment, including Mood Disorders, especially Bipolar, Anxiety Disorders, and addictions. Chapters on pharmacological treatments for Eating Disorders, Attention Deficit Disorder, Autism and Asperger’s Syndrome, and Impulse Control Disorder represent the latest thinking on these subjects. The final Section contains a consummate example of out-of-the [Western]- box thinking, namely consideration of herbal medicines – used by a large number of patients, with or without medical supervision. We conclude with a close look at the problem of side effects, then selected thoughts about methodology. Clearly written, the text provides immediate access to new developments across the spectrum of drug testing. Clinical Trials in Psychopharmacology: A Better Brain is provocative reading for psychiatrists, pharmacologists and all those interested in improved drug treatments for patients with mental illness. Raises questions about the conduct of trials and the credibility of their outcomes that are relevant not just in psychiatry but all areas of medicine Discusses the ethical problems in assessing outcomes in humans, including children...

DOWNLOAD
Author by : Marc Hertzman
Languange Used : en
Release Date : 1997-06
Publisher by : NYU Press

ISBN : 0814735320

Each year pharmaceutical companies invest billions of dollars in clinical trials of drugs used for the treatment of central nervous system diseases. Due to enormous progress in basic pharmaceutical research in recent years, controlled tests of new medications are flourishing and these trials have rapidly become an intense focus of practical medical research. Aware of the complexities presented in the design, execution, and evaluation of clinical trials, Marc Hertzman and Douglas E. Feltner bring together a collection of essays that dissect the scientific, psychosocial, political, and ethical concerns that must be examined for any CNS trial. The internationally known contributors examine concerns about ethics and cost; the FDA and its regulatory impact; and the implementation of a variety of trials, for disorders such as schizophrenia, alcoholism, eating disorders, insomnia, and aggression. The editors carefully consider important social issues including the considerations related to women's special needs; and the relative merits of psychotherapy and medications. The Handbook of Psychopharmocology Trials provides an up-to- date and stimulating exploration of important issues on the subject of CNS Clinical trials....

DOWNLOAD
Author by : Ian M. Anderson
Languange Used : en
Release Date : 2004-09-20
Publisher by : CRC Press

ISBN : 9781841844275

This book brings together leading UK psychiatrists and psychopharmacologists to review and clarify essential information about the scientific background and clinical applications of the drugs used in psychiatry. Based on the excellent Psychopharmacology Course for Psychiatrists in Training, organized twice a year by the British Association for Psychopharmacology, Fundamentals of Clinical Psychopharmacology reflects the individual lectures that make up the course, ranging from basic neuroscience to the analysis of clinical trials. The book is updated regularly, and this Second Edition includes a helpful new chapter on child and adolescent psychopharmacology....

DOWNLOAD
Author by : Peter Lydyard
Languange Used : en
Release Date : 2015-08-18
Publisher by : CRC Press

ISBN : 9781040084861

This book provides up-to-date, evidence-based and unbiased information about psychopharmacology. It spans the range of the discipline, from mode of action and side effects of drugs to meta-analyses of clinical trials. This latest edition is fully updated and provides the key facts about currently used psychotropic drugs, set in the context of the neuroscience of the disorders they treat. It also includes a new chapter on the principles of psychiatric prescribing. Key references are provided at the end of each chapter along with suggestions for further reading....

DOWNLOAD
Author by : Dan J. Stein
Languange Used : en
Release Date : 2005-07-21
Publisher by : Cambridge University Press

ISBN : 0521824818

This book summarizes the recent advances in evidence-based pharmacological treatment of psychiatric disorders....

DOWNLOAD
Author by : National Institute of Mental Health (U.S.)
Languange Used : en
Release Date : 1973
Publisher by :

ISBN : OSU:32435026800847

...

DOWNLOAD
Author by : Ian M. Anderson
Languange Used : en
Release Date : 2015-08-31
Publisher by : CRC Press

ISBN : 1498718949

Fundamentals of Clinical Psychopharmacology provides up-to-date, evidence-based and unbiased information about psychopharmacology. It spans the range of the discipline, from mode of action and side effects of drugs to meta-analyses of clinical trials. It is anchored to practice guidelines produced by the UK National Institute for Health and Care Excellence (NICE) and the British Association for Psychopharmacology (BAP). Care has been taken to provide an international perspective that makes it equally useful to practitioners in the US and other countries. The book grew out of BAP courses that set the standard for professional psychopharmacological education in the UK. This latest edition is fully updated and provides, in a concise and easy-to-read format, key facts about currently used psychotropic drugs, set in the context of the neuroscience of the disorders they treat. It also includes a new chapter on the principles of psychiatric prescribing. Key references, including the clinical studies discussed, are provided at the end of the chapter along with suggestions for further reading. Intended to be a frequently updated, affordable, concise and practical resource, it meets the needs of trainees and practitioners seeking to keep abreast of the state of the art in psychopharmacology....

DOWNLOAD
Author by : Robert Haim Belmaker
Languange Used : en
Release Date : 2023-10-18
Publisher by : Springer Nature

ISBN : 9783031403712

This thought-provoking book covers the full range of psychopharmacologic practice in textbook fashion, offering a fresh and comprehensive self-examination. Unlike conventional texts of psychopharmacology, this text speaks directly to clinicians who have started to question the limitations of psychopharmacologic claims and the rigid confines of DSM-5 diagnoses. Drawing from their clinical and research experience as well as new literature, the well-published authors provide a new perspective that encourages readers to reevaluate established practices and embrace that medication is just one component of treatment and has limits. The book could be used by psychiatric residents in their course of study, by clinical psychology students taking a psychopharmacology course, or by psychiatrists curious to get a readable but comprehensive look at new critical viewpoints in psychopharmacology that have changed since they were taught. Many neuroscience students who are looking for a review of clinical effects to guide their basic research may also find the proposed text more useful than those texts that collate clinical trials. Current texts are for specialized scientists or are part of multi-authored texts which list drugs alphabetically with no conceptual framework, or books that pretend that each biochemical drug property has a clear and known clinical result presented in cartoon style. Some lesser known texts for psychology or nursing students are not authoritative. Others aimed at patients or families are too simplistic for clinicians. The authors’ goal was to create a unified text expressing their view of psychopharmacology, its evidence base, the unity of its essential principles, and its independence of DSM or ICD diagnosis. Several new history books describe the "rise and fall" of psychopharmacology, the corruption of big pharma and the failure of large controlled clinical trials. Psychopharmacology Reconsidered: A Concise Guide Exploring the Limits of Diagnosis and Treatment ensures that young clinicians are aware of and understand this critical zeitgeist but aware also of the essential core of psychopharmacology and the evidence upon which it rests....

DOWNLOAD
Author by : Ian M. Anderson
Languange Used : en
Release Date : 2019-02-13
Publisher by : CRC Press

ISBN : 9780203448304

In the rapidly changing field of pharmacology, it is essential that all those involved in the prescribing or administering of medication to people with mental disorders keep up to date with the latest developments. This book is based on the highly successful course for trainee psychiatrists held twice yearly in Great Britain. Leading psychiatrists...