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Deep Brain Stimulation

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Author by : Kendall H. Lee
Languange Used : en
Release Date : 2016-12-08
Publisher by : CRC Press

ISBN : 9781315341095

Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood. Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation–evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery....

Deep Brain Stimulation

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Author by : William S. Anderson
Languange Used : en
Release Date : 2019-05-10
Publisher by : Thieme

ISBN : 9781626237988

The one-stop resource on deep brain stimulation for functional neurosurgeons! Deep brain stimulation (DBS) is used to modulate dysfunctional circuits in the brain with stimulation pulses applied to specific target areas of the brain. Globally, DBS procedures have been most commonly performed for Parkinson's disease and essential tremor, but there are now new and growing research efforts studying DBS for psychiatric disorders and epilepsy. Deep Brain Stimulation: Techniques and Practices written by the Society for Innovative Neuroscience in Neurosurgery along with Dr. William S. Anderson and distinguished experts presents the latest DBS approaches. The book begins with a history of DBS, general frame-based techniques, patient selection primarily for movement disorders, multidisciplinary collaboration, and ethical considerations. Subsequent chapters detail diverse technologies and disease-specific treatment for Parkinson's disease, essential tremor, dystonia, OCD, epilepsy, major depression, Tourette syndrome, emerging psychiatric indications, and pediatric applications. Key highlights Lead placement techniques utilizing currently available customized platforms and robotics Microelectrode recording and image-based direct targeting with MRI and CT to enhance lead placement Lesioning methods including radiofrequency, and MR-guided focused ultrasound Discussion of recent innovations in tractography to delineate white matter tracts in the brain and closed loop stimulation DBS has helped thousands of patients with intractable conditions, allowing for a programmable therapy with durable treatment effect. This remarkable guide provides the essentials for functional neurosurgeons to pursue intraoperative research opportunities in this growing subspecialty and incorporate DBS into clinical practice....

Deep Brain Stimulation Programming

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Author by : Erwin B. Montgomery (Jr.)
Languange Used : en
Release Date : 2010-04-13
Publisher by : Oxford University Press

ISBN : 9780199738526

The book is a guide to the principles of electronics, electrophysiology and regional neuroanatomy that allows the rational use of Deep Brain Stimulation. Practical issues are addressed and algorithms and tools are provided. Also, how DBS is leading to new and revolutionary theories of brain function and dysfunction are described....

Deep Brain Stimulation For Neurological Disorders

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Author by : Toru Itakura
Languange Used : en
Release Date : 2014-08-28
Publisher by : Springer

ISBN : 9783319084763

Chronic electrical stimulation of the brain has demonstrated excellent outcomes in patients with Parkinson’s disease and has recently also been applied to various other neurological diseases. This comprehensive, up-to-date textbook will meet the needs of all who wish to learn more about the application of deep brain stimulation and will provide a sound basis for safe and accurate surgery. The book comprises two main parts, the first of which presents relevant anatomical and functional background information on the basal ganglia, thalamus and other brain structures as well as on the mechanism of brain stimulation. The second part describes clinical studies on deep brain stimulation, covering results in a range of movement disorders and psychiatric diseases and also important aspects of instrumentation and technique. The authors are outstanding scientists and experts in the field from across the world....

Deep Brain Stimulation

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Author by : Shilpa Chitnis MD, PhD
Languange Used : en
Release Date : 2020-06-30
Publisher by : Oxford University Press

ISBN : 9780190647223

DEEP BRAIN STIMULATION provides expert advice to the reader on selection guidelines and programming techniques for straight-forward as well as for challenging case management in movement and neuropsychiatric disorders. The collection offers a broad DBS experience that is delivered directly to you by leaders in neuromodulation. There are both common and uncommon case presentations and each case is accompanied by a literature review and pearls to improve your practice. The book improves fundamental DBS techniques as well as expands the skills necessary for troubleshooting more difficult presentations. The case-based problem-solving approach makes this a fun and practical read....

Deep Brain Stimulation Management

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Author by : William J. Marks, Jr
Languange Used : en
Release Date : 2015-09-03
Publisher by : Cambridge University Press

ISBN : 9781107084254

Essential reference guide for clinicians working with DBS patients, fully revised throughout with new chapters on epilepsy and psychiatric disorders....

Deep Brain Stimulation For Parkinson S Disease

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Author by : Gordon H. Baltuch
Languange Used : en
Release Date : 2007-03-19
Publisher by : CRC Press

ISBN : 9781420019759

Considered the largest breakthrough in the treatment of Parkinson's disease in the past 40 years, Deep Brain Stimulation (DBS) is a pioneering procedure of neurology and functional neurosurgery, forging enormous change and growth within the field. The first comprehensive text devoted to this surgical therapy, Deep Brain Stimulation for Parkinson's...

Brain Stimulation

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Author by : Filippo Agnesi
Languange Used : en
Release Date : 2013-11-11
Publisher by : Elsevier Inc. Chapters

ISBN : 9780128080108

Chronic deep brain stimulation (DBS) has become a widely accepted surgical treatment for medication-refractory movement disorders and is under evaluation for a variety of neurological disorders. In order to create opportunities to improve treatment efficacy, streamline parameter selection, and foster new potential applications, it is important to have a clear and comprehensive understanding of how DBS works. Although early hypothesis proposed that high-frequency electrical stimulation inhibited neuronal activity proximal to the active electrode, recent studies have suggested that the output of the stimulated nuclei is paradoxically activated by DBS. Such regular, time-locked output is thought to override the transmission of pathological bursting and oscillatory activity through the stimulated nuclei, as well as inducing synaptic plasticity and network reorganization. This chapter reviews electrophysiological experiments, biochemical analyses, computer modeling and imaging studies positing that, although general principles exist, the therapeutic mechanism(s) of action depend both on the site of stimulation and on the disorder being treated....

20 Things To Know About Deep Brain Stimulation

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Author by : Erwin B. Montgomery, Jr.
Languange Used : en
Release Date : 2015-01-02
Publisher by : Oxford University Press

ISBN : 9780199338832

Twenty Things to Know About Deep Brain Stimulation is an extensive and in-depth critical analysis of the field of Deep Brain Stimulation (DBS) from what many may consider a revolutionary perspective. This book demonstrates the unique nature and incredible promise of DBS and shows how it is unparalleled as a therapeutic intervention. Dr. Montgomery provides an epistemic analysis of the presuppositions, assumptions and fallacies underlying current clinical understanding of DBS as well as the physiology and pathophysiology affected by DBS. Reviews of the safety and efficacy for a number of conditions, patient selections and issues in the post-operative management are also included. Given the revolutionary potential and the complexity of DBS in an ever changing healthcare delivery context, the ethics of DBS are discussed in detail....

Fundamentals And Clinics Of Deep Brain Stimulation

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Author by : Yasin Temel
Languange Used : en
Release Date : 2020-03-24
Publisher by : Springer Nature

ISBN : 9783030363468

This book provides a state-of-the-art overview of our current understanding of deep brain stimulation (DBS) for the treatment of neurological and psychiatric disorders. With a broad multidisciplinary scope, it presents contributions from leading experts in the field from Europe and America, who share not only their knowledge, but their experience as well. The book focuses both on basic and theoretical aspects of DBS, as well as clinical and practical aspects. It follows an evidence-based approach, and where possible offers clinical recommendations based on published guidelines. It starts with a general section, which discusses basic principles and general considerations. This is followed a sections dedicated to neurological disorders, and psychiatric disorders, in which only accepted indications are discussed. All experimental indications are discussed in the final chapter. The text is supplemented with numerous illustrations. Intended for medical specialists and residents involved in the treatment of patients with DBS, it also appeals to other professionals working with DBS patients, such as psychologists, nurses, physiotherapists, as well as basic and clinical neuroscientists....