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Clinical Trials In Psychiatry

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Author by : Brian S. Everitt
Languange Used : en
Release Date : 2008-04-15
Publisher by : John Wiley & Sons

ISBN : 047072384X

At last – a new edition of the highly acclaimed book Clinical Trials in Psychiatry This book provides a concise but thorough overview of clinical trials in psychiatry, invaluable to those seeking solutions to numerous problems relating to design, methodology and analysis of such trials. Practical examples and applications are used to ground theory whenever possible. The Second Edition includes new information regarding: Recent important psychiatric trials More specific discussion of psychiatry in the USA and the particular problems of trials in the USA, including comments about the FDA (U.S. Food and Drug Administration) An extended chapter on meta-analysis Further discussion of sub-group analysis Special features include appendices outlining how to design and report clinical trials, what websites and software programs are appropriate and an extensive reference section. From the reviews of the First Edition: “Everitt & Wessely are to be congratulated on producing an excellent guide to help overcome the snags in clinical trial research. Clearly written and in an engrossing style, the book is likely to become a classic textbook on clinical trials, and not just in psychiatry. The authors’ enthusiasm and grasp of clinical trial research make for a gripping and insightful read...it is one of the very best books that has been written on clinical trials.” THE BRITISH JOURNAL OF PSYCHIATRY "The experience of both authors in this area gives the book a very pragmatic approach grounded in reality, with theoretical overviews invariably being followed by practical examples and applications... an invaluable companion to anyone involved in, or contemplating undertaking, clinical trials research.” PSYCHOLOGICAL MEDICINE...

50 Studies Every Psychiatrist Should Know

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Author by : Ish P. Bhalla
Languange Used : en
Release Date : 2018
Publisher by : Oxford University Press

ISBN : 9780190625085

50 Studies Every Psychiatrist Should Know presents key studies that have shaped the practice of psychiatry. Selected using a rigorous methodology, the studies cover topics including: psychotic disorders, depressive disorders, women's mental health, child and adolescent disorders, and epidemiological studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice....

Clinical Trials In Psychopharmacology

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Author by : Marc Hertzman
Languange Used : en
Release Date : 2010-03-16
Publisher by : John Wiley & Sons

ISBN : 0470749172

Although clinical trials were virtually unheard of in psychiatry for many years, they are now the gold standard for judging whether drugs are safe and useful. But should they be? What is the true status of clinical trials? Even when they ostensibly demonstrate a benefit of a certain treatment, the strict patient selection criteria, poor compliance and high drop-out rate leave the conclusions open to question. Are the new treatments really better or more cost-effective than the old? Do they have fewer side effects? In this book the authors take a critical look at recent developments and present a series of trenchant and challenging observations. Section I examines the significant changes in law and the regulatory environment that have occurred during the past ten years. Has fossilization handicapped the US Food and Drug Administration in promoting treatment advances? How can the plethora of findings be regulated? This is particularly pertinent in genomic studies and there are two chapters addressing the impact of genomics on psychiatric research. This section also addresses the role of women in drug trials – a group long excluded but now demanding a part, for without testing how can optimal treatments be devised? The next two Sections highlight clinical trials in the major areas of psychiatric pharmacological treatment, including Mood Disorders, especially Bipolar, Anxiety Disorders, and addictions. Chapters on pharmacological treatments for Eating Disorders, Attention Deficit Disorder, Autism and Asperger’s Syndrome, and Impulse Control Disorder represent the latest thinking on these subjects. The final Section contains a consummate example of out-of-the [Western]- box thinking, namely consideration of herbal medicines – used by a large number of patients, with or without medical supervision. We conclude with a close look at the problem of side effects, then selected thoughts about methodology. Clearly written, the text provides immediate access to new developments across the spectrum of drug testing. Clinical Trials in Psychopharmacology: A Better Brain is provocative reading for psychiatrists, pharmacologists and all those interested in improved drug treatments for patients with mental illness. Raises questions about the conduct of trials and the credibility of their outcomes that are relevant not just in psychiatry but all areas of medicine Discusses the ethical problems in assessing outcomes in humans, including children...

Clinical Trials In Psychiatry

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Author by :
Languange Used : en
Release Date :
Publisher by :

ISBN : OCLC:1394046589

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Research Methods In Psychiatry

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Author by : Chris Freeman
Languange Used : en
Release Date : 2006-12
Publisher by : RCPsych Publications

ISBN : 1904671330

This updated comprehensive guide to psychiatric research methods takes the reader from getting started in research through to publishing a paper, with advice on avoiding common pitfalls along the way. Systematic analysis and meta-analysis, epidemiology, qualitative research, and research focused on a few patients are discussed, together with the principles of validity and reliability in the assessment of psychological variables and statistical aspects of the design and analysis of clinical trials. Five completely new chapters cover topics such as research from the trainee's perspective and research in learning disability and child and adolescent psychiatry. A key text for psychiatric trainees embarking on research projects, this book will also be useful to psychiatrists supervising research projects, and those in the social sciences with an interest in carrying out research or critically reviewing the published evidence. Topics covered include setting up a research project, how to make a comprehensive review of the literature, choosing a rating scale, and getting research published....

Clinical Trials In Psychiatry

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Author by : Brian Everitt
Languange Used : en
Release Date : 2023
Publisher by :

ISBN : 1383024421

'Clinical Trials in Psychiatry' explains RCTs for mental health professionals. It starts by discussing why we need trials and why they are the best way of deciding if a treatment works. It then describes the different types of trial, how to analyze the results, and how to conduct a trial....

Global Mental Health Trials

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Author by : Graham Thornicroft
Languange Used : en
Release Date : 2014
Publisher by : Oxford University Press, USA

ISBN : 9780199680467

Global Mental Health Trials brings together many of the world's leading researchers active in the fields of Randomised Control Trials in low- and medium-resource counties and settings related to improving mental health care....

On Trial

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Author by : Marietta Meier
Languange Used : en
Release Date : 2024-07-30
Publisher by :

ISBN : 1526169800

The book offers a deep insight into the early days of industry-sponsored clinical research in psychiatry. Examining how the clinic, patients, doctors, nursing staff, corporations, and authorities interacted, it not only meticulously reconstructs the experimental practices in a psychiatric hospital from 1940 to 1980 but also tells a larger story: the changing history of clinical trials....

Elements Of Clinical Research In Psychiatry

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Author by : James Edward Mitchell
Languange Used : en
Release Date : 2000
Publisher by : American Psychiatric Pub

ISBN : UOM:39015042484314

Clinical research is often thought of as a dry and somewhat arcane pursuit. Not so, assert the editors of Elements of Clinical Research in Psychiatry. The editors, all actively engaged in clinical research, bring this topic to life by combining a boundless enthusiasm for their chosen field with a depth of knowledge rarely seen in the literature. They show that clinical research can be rewarding not only because the research results contribute to improving the welfare of psychiatric patients, but also because the research process itself is exciting. Arguably the definitive guidebook on clinical psychiatric research, this volume discusses * Careers in clinical mental health research -- Describes what clinical psychiatric researchers do and how to get started on this career path. * Research design, measurement, and assessment -- Covers all aspects of research design, defines and evaluates measurement types, and details various assessment methods (from interviews and questionnaires to lab tests and brain images). * Descriptive and inferential statistics -- Shows how statistics are used to analyze and summarize measurement data. * Research support -- Provides a roadmap for those seeking research support in the U.S. (more than 90% is funded via NIH), detailing how to write grants from the ground up. * Use of human subjects (the Institutional Review Board [IRB]) and ethics and misconduct -- Demystifies the often intimidating process of seeking and receiving IRB approval, with tips on how to work with the IRB and complete its consent forms; uses a series of practical scenarios, including a highly publicized case of alleged misconduct, to illustrate complex ethics and misconduct issues. * Writing journal articles, reviewing manuscripts, and giving scientific presentations -- Presents the nuts and bolts of publishing journal articles; gives step-by-step advice for reviewing manuscripts and giving oral presentations, symposia, poster sessions, and colloquia. Carefully chosen appendixes provide readers with additional information they can use right away, augmented by an index and detailed reference list for further investigation. Anyone considering clinical psychiatric research as a career option will find in this succinct and eminently practical volume the single source they need. Practicing psychiatrists interested in specific areas of clinical research, such as human subject use or biomedical ethics, will also find much of interest here. Replete with useful information, these stimulating discussions provide the building blocks for embarking upon -- and enhancing -- a successful career in clinical psychiatric research....

Neuroscience Trials Of The Future

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Author by : National Academies of Sciences, Engineering, and Medicine
Languange Used : en
Release Date : 2016-11-07
Publisher by : National Academies Press

ISBN : 9780309442589

On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future....